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Hint

  • The vesicles could be imaged, e.g. with electron microscopy, to get an independent estimation of its structure, number of layers, polydispersity etc.
  • Chemical assays could be used to determine the lipid content.
      • Some ideas for improving the models:
    • The model contains no information about the shape of the vesicle, it only assumes that is contains one (unilamellar) many layers (multilamellar), and assumes that the vesicles are infinitely large (radius->inf) - maybe a finite vesicle radius could be build into the model?
    • The overall size may be determined with, e.g. dynamic light scattering or other biophysical techniques.
    • There may be a layer of water around the lipids with a slightly different density than bulk water - this could be build into the model.
        • Some ideas specifically for the multipamellar model (lamellar_hg_stack_caille):
      • There may be polydispersity in the model (not all particles are the same). E.g. they may contain different number of layers (polydispersity in the parameter Nlayers).
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